Pressure vessel plays an important role in wide range of applications to store gas or liquid substances. In order to design a pressure vessel safely, one of the main factors which has to be considered is selection of proper burst pressure perdition criterion. Due to large range of available materials in manufacturing of the vessels under different working conditions, several criteria to forecast burst pressure of the vessels have been developed and used by designers. Choosing the most proper criterion based on working condition and the material is a vital task to meet design requirements because inappropriate criterion may lead to unsafe vessel or over design. This issue makes not only pressure vessel design more complex but also maintenance planning, especially for designers who do not have enough experience, is a challenging task. Therefore, lack of a burst pressure predictor model, which is able to determine the pressure more accurately for wide range of materials and applications, has been remained unsolved. To evaluate machine learning techniques in prediction of burst pressure of pressure vessels, in this paper, a new model based on artificial neural network (ANN) has been proposed and developed. Input parameters of the model include internal and outer diameter, thickness, ultimate and yield strength; output is burst pressure. The obtained results showed that the constructed model has a good potential to be used as more applicable model compared to current models in design of pressure vessels.