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Journal Articles

Development of a Recombinase Polymerase Amplification Assay on Digital Microfluidics for Point-of-Care Detection of Plasmodium falciparum

Yen Khanh Ngo, Doan Hong Ngoc Tran, Ngoc Phuong Uyen Nguyen, Trieu Man Huynh, Tuan Hoang, Thien Hoang, Thi Hoang Nghi Mai, Toi Van Vo, Minh Nam Nguyen, Khon Huynh
Journal: Journal of Medical Devices
Publisher: ASME
Article Type: Technical Briefs
J. Med. Devices. June 2025, 19(2): 024502.
Paper No: MED-24-1063
https://doi.org/10.1115/1.4067264
Published Online: December 16, 2024
...-of-care (POC) application. To overcome those drawbacks, we developed a colorimetric recombinase polymerase amplification (RPA) reaction on a digital microfluidic (DMF) platform using SYBR Green I as the indicator for a simple result readout step, thus simplifying the diagnostic procedure. Using primers...
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Topics: Drops, Microfluidics