A patient-specific seizure prediction algorithm is proposed using a classifier to differentiate pre-ictal from inter-ictal EEG signals. The spectral power of EEG processed in four different fashions is used as features: raw, time-differential, space-differential, and time/space-differential EEG. The features are classified using cost-sensitive support vector machines by the double cross-validation methodology. The proposed algorithm has been applied to EEG recordings of 18 patients in the Freiburg EEG database, totaling 80 seizures and 437 h long inter-ictal recordings. Classification with the feature obtained from time/space-differential ECoG demonstrates the performance of 86.25% sensitivity and 0.1281 false positives per hour in out-of-sample testing.
Seizure Prediction With Spectral Power of EEG Using Cost-Sensitive Support Vector Machines
Park, Y., Netoff, T., and Parhi, K. (August 12, 2010). "Seizure Prediction With Spectral Power of EEG Using Cost-Sensitive Support Vector Machines." ASME. J. Med. Devices. June 2010; 4(2): 027542. https://doi.org/10.1115/1.3455144
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