In this paper, the influence of chemical reaction and heat source/sink on an unsteady magnetohydrodynamics (MHD) nanofluid flow that squeezed between two radiating parallel plates embedded in porous media is investigated analytically. We consider water as base fluid and aluminum oxide () as its nanoparticle. We reduced the basic partial differential equations to ordinary differential equations which are solved by the homotopy analysis method (HAM). The effects of the squeeze number, permeability parameter of porous media, Hartmann number, thermal radiation parameter, Prandtl number, heat source/sink parameter, Eckert number, Schmidt number, and scaled parameter of chemical reaction on the flow, heat, and mass transfer are considered and assigned to graphs. The physical quantities such as Sherwood number, Nusselt number, and skin friction coefficient are computed for –water, –water, –water, and –water nanofluids and assigned through graphs.