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Keywords: elastin
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Journal Articles
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081008.
Paper No: BIO-21-1330
Published Online: March 11, 2022
...Abhay B. Ramachandra; Nicole Mikush; Maor Sauler; Jay D. Humphrey; Edward P. Manning Competent elastic fibers are critical to the function of the lung and right circulation. Murine models of elastopathies can aid in understanding the functional roles of the elastin and elastin-associated...
Includes: Supplementary data
Journal Articles
Article Type: Research-Article
J Biomech Eng. June 2019, 141(6): 061002.
Paper No: BIO-18-1132
Published Online: April 22, 2019
...P. Mythravaruni; Parag Ravindran Oxidation of aorta by hydroxyl radicals produces structural changes in arterial proteins like elastin and collagen. This in turn results in change in the mechanical response of aorta. In this paper, a thermodynamically consistent constitutive model is developed...
Journal Articles
Article Type: Technical Briefs
J Biomech Eng. April 2019, 141(4): 044504.
Paper No: BIO-18-1348
Published Online: February 25, 2019
...Jessica E. Wagenseil Allometric scaling laws relate physiologic parameters to body weight. Genetically modified mice allow investigation of allometric scaling laws when fundamental cardiovascular components are altered. Elastin haploinsufficient (Eln +/− ) mice have reduced elastin amounts...
Journal Articles
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021028.
Paper No: BIO-13-1428
Published Online: February 5, 2014
... collagen elastin ATAA are dilatations of the arterial wall that result primarily from a weakening in the middle smooth muscle layer, or media, of the artery [ 1–3 ]. Aneurysm dissection and rupture pose serious risk of mortality and are the primary concerns for patients with an ATAA [ 1–4...
Journal Articles
Article Type: Design Innovations
J Biomech Eng. July 2011, 133(7): 075001.
Published Online: July 29, 2011
... testing microstructure mechanical collagen elastin mouse aorta two-photon multiphoton The use of genetically modified mice has proven to be a valuable addition to the study of disease etiology and treatment. Particularly, these mouse models for disease provide a means to test disease...
Journal Articles
Article Type: Research Papers
J Biomech Eng. July 2011, 133(7): 071007.
Published Online: July 18, 2011
... to model and predict the behavior under any load. Most ex vivo tests are performed within 24 h of dissection, so the tissue is still “alive.” For large elastic arteries; however, the passive mechanical behavior is attributed mostly to the very stable proteins, elastin, and collagen. If the testing...
Journal Articles
Article Type: Research Papers
J Biomech Eng. October 2009, 131(10): 101018.
Published Online: October 14, 2009
...Silvia Wognum; David E. Schmidt; Michael S. Sacks The urinary bladder wall (UBW), which is composed of smooth muscle, collagen, and elastin, undergoes profound remodeling in response to changes in mechanical loading resulting from various pathologies. In our laboratory, we have observed...
Journal Articles
Article Type: Research Papers
J Biomech Eng. June 2008, 130(3): 031017.
Published Online: May 6, 2008
... for the individual contribution of each major structural component (elastin, collagen, and vascular smooth muscle). However, none of the currently proposed structural models succeeded in simultaneously and accurately describing both the pressure-radius and pressure-longitudinal force curves. We have hypothesized...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. August 2007, 129(4): 611–618.
Published Online: January 24, 2007
... system biomechanics physiological models elasticity proteins molecular biophysics molecular configurations finite element method collagen elastin network The mechanical behavior of the arterial wall is central to hemodynamic and vascular health. Clinical treatments (e.g., arterial...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. June 2006, 128(3): 409–418.
Published Online: November 16, 2005
... 2005 biomechanics neurophysiology muscle mechanoception strain energy function (SEF) material parameters collagen elastin The primary function of the esophagus is food transport facilitated by the peristaltic motion of muscle, which is mainly a mechanical process. In order...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. December 2002, 124(6): 724–733.
Published Online: December 27, 2002
... and untreated TEBVs were measured following 1, 7, 15, 30, 45, and 60 days of treatment. At corresponding time points, the effect of these treatments on collagen and elastin protein synthesis and mRNA expression was examined. RA/AA treated TEBV strength increased and stiffness decreased compared to controls...