...Frank E. Fresconi; Ajay K. Prasad The adverse health effects of inhaled particulate matter from the environment depend on its dispersion, transport, and deposition in the human airways. Similarly, precise targeting of deposition sites by pulmonary drug delivery systems also relies on characterizing...

...Frank E. Fresconi; Ajay K. Prasad An understanding of flow and dispersion in the human respiratory airways is necessary to assess the toxicological impact of inhaled particulate matter as well as to optimize the design of inhalable pharmaceutical aerosols and their delivery systems. Secondary flows...

... numerical model. The model was validated by running interferometric Mie imaging experiments using test droplets with nonvolatile content, which formed droplet nuclei, ultimately, in a class-100 clean-room chamber. By comparing the droplet dispersion and removal characteristics with data of two other ceiling...

...Srinath Madasu; Ali Borhan; James S. Ultman In conventional one-dimensional single-path models, radially averaged concentration is calculated as a function of time and longitudinal position in the lungs, and coupled convection and diffusion are accounted for with a dispersion coefficient...