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Journal Articles

A Novel Port to Facilitate Magnetic Hyperthermia Therapy for Glioma

Benjamin Rodriguez, Peter Campbell, Joseph Borrello, Ian Odland, Tyree Williams, Eugene I. Hrabarchuk, Tirone Young, Anirudh Sharma, Alexander J. Schupper, Benjamin Rapoport, Robert Ivkov, Constantinos Hadjipanayis
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2024, 146(1): 011009.
Paper No: BIO-23-1207
https://doi.org/10.1115/1.4063556
Published Online: November 22, 2023
View Article titled, A Novel Port to Facilitate Magnetic Hyperthermia Therapy for Glioma
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Topics: Brain, Design, Iron, Nanoparticles, Patient treatment, Phantoms, Physiology, Tumors, Temperature, Biological tissues
Journal Articles

Using Parallel Coordinates in Optimization of Nano-Particle Drug Delivery

Timoleon Kipouros, Ibrahim Chamseddine, Michael Kokkolaras
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. April 2022, 144(4): 044501.
Paper No: BIO-21-1174
https://doi.org/10.1115/1.4052578
Published Online: November 5, 2021
View Article titled, Using Parallel Coordinates in Optimization of Nano-Particle Drug Delivery
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Topics: Design, Drug delivery systems, Nanoparticles, Optimization, Tumors, Modeling, Drugs
Journal Articles

Improving Pulmonary Nanotherapeutics Using Helical Aerosol Streams: An In Silico Study

Adithya Gurumurthy, Clement Kleinstreuer
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2021, 143(11): 111001.
Paper No: BIO-21-1035
https://doi.org/10.1115/1.4051217
Published Online: July 14, 2021
View Article titled, Improving Pulmonary Nanotherapeutics Using Helical Aerosol Streams: An In Silico Study
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Topics: Aerosols, Drugs, Flow (Dynamics), Nanoparticles, Particulate matter, Lung, Diffusion (Physics), Fluids, Drug delivery systems
Journal Articles

Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia

Peiyuan Kang, Chen Xie, Oumar Fall, Jaona Randrianalisoa, Zhenpeng Qin
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2021, 143(3): 031004.
Paper No: BIO-20-1113
https://doi.org/10.1115/1.4049017
Published Online: December 10, 2020
View Article titled, Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia
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Topics: Heating, Nanoparticles, Proteins, Temperature, Materials properties, Lasers, Shapes
Includes: Supplementary data
Journal Articles

A Dual Nanoparticle Delivery Strategy for Enhancing Drug Distribution in Cancerous Tissue

Ibrahim M. Chamseddine, Michael Kokkolaras
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. December 2020, 142(12): 124501.
Paper No: BIO-19-1462
https://doi.org/10.1115/1.4047657
Published Online: September 8, 2020
View Article titled, A Dual Nanoparticle Delivery Strategy for Enhancing Drug Distribution in Cancerous Tissue
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Topics: Drugs, Nanoparticles, Tumors, Biological tissues, Optimization
Journal Articles

Nanoparticle Optimization for Enhanced Targeted Anticancer Drug Delivery

Ibrahim M. Chamseddine, Michael Kokkolaras
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2018, 140(4): 041002.
Paper No: BIO-17-1243
https://doi.org/10.1115/1.4038202
Published Online: January 19, 2018
View Article titled, Nanoparticle Optimization for Enhanced Targeted Anticancer Drug Delivery
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Topics: Drugs, Nanoparticles, Optimization, Tumors, Design, Vessels, Shapes
Journal Articles

Thermomechanical Stress in Cryopreservation Via Vitrification With Nanoparticle Heating as a Stress-Moderating Effect

David P. Eisenberg, John C. Bischof, Yoed Rabin
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2016, 138(1): 011010.
Paper No: BIO-15-1343
https://doi.org/10.1115/1.4032053
Published Online: December 8, 2015
View Article titled, Thermomechanical Stress in Cryopreservation Via Vitrification With Nanoparticle Heating as a Stress-Moderating Effect
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Topics: Cryonics, Heating, Nanoparticles, Stress, Temperature, Thermomechanics, Vitrification, Cooling, Heat transfer, Crystallization
Journal Articles

Influence of Hyperthermia on Efficacy and Uptake of Carbon Nanohorn-Cisplatin Conjugates

Matthew R. DeWitt, Allison M. Pekkanen, John Robertson, Christopher G. Rylander, Marissa Nichole Rylander
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021003.
Paper No: BIO-13-1471
https://doi.org/10.1115/1.4026318
Published Online: February 5, 2014
View Article titled, Influence of Hyperthermia on Efficacy and Uptake of Carbon Nanohorn-Cisplatin Conjugates
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Topics: Carbon, Drugs, Heat, Nanoparticles, Tumors, Temperature, Heating, Particulate matter, Patient treatment, Diffusion (Physics)
Journal Articles

Nanoparticle Mass Transfer From Lung Airways to Systemic Regions—Part I: Whole-Lung Aerosol Dynamics

Arun V. Kolanjiyil, Clement Kleinstreuer
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2013, 135(12): 121003.
Paper No: BIO-13-1174
https://doi.org/10.1115/1.4025332
Published Online: October 9, 2013
View Article titled, Nanoparticle Mass Transfer From Lung Airways to Systemic Regions—Part I: Whole-Lung Aerosol Dynamics
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Topics: Dynamics (Mechanics), Flow (Dynamics), Lung, Nanoparticles, Particulate matter, Fluids
Journal Articles

Nanoparticle Mass Transfer From Lung Airways to Systemic Regions—Part II: Multi-Compartmental Modeling

Arun V. Kolanjiyil, Clement Kleinstreuer
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2013, 135(12): 121004.
Paper No: BIO-13-1175
https://doi.org/10.1115/1.4025333
Published Online: October 9, 2013
View Article titled, Nanoparticle Mass Transfer From Lung Airways to Systemic Regions—Part II: Multi-Compartmental Modeling
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Topics: Lung, Nanoparticles, Particulate matter, Modeling, Clearances (Engineering), Mass transfer
Journal Articles

Hydrodynamic Modeling of Targeted Magnetic-Particle Delivery in a Blood Vessel

Huei Chu Weng
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. March 2013, 135(3): 034504.
Paper No: BIO-12-1411
https://doi.org/10.1115/1.4023137
Published Online: February 11, 2013
View Article titled, Hydrodynamic Modeling of Targeted Magnetic-Particle Delivery in a Blood Vessel
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Topics: Biomedicine, Blood vessels, Flow (Dynamics), Magnetic fields, Magnetic fluids, Magnetic particles, Modeling, Nanoparticles, Particulate matter, Drag (Fluid dynamics)
Journal Articles

Theoretical Study on Temperature Dependence of Cellular Uptake of QDs Nanoparticles

Aili Zhang, Yingxue Guan, Lisa X. Xu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. December 2011, 133(12): 124502.
https://doi.org/10.1115/1.4005481
Published Online: December 21, 2011
View Article titled, Theoretical Study on Temperature Dependence of Cellular Uptake of QDs Nanoparticles
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Topics: Fluorescence, Nanoparticles, Temperature, Cell membranes
Journal Articles

Modeling Material-Degradation-Induced Elastic Property of Tissue Engineering Scaffolds

N. K. Bawolin, M. G. Li, X. B. Chen, W. J. Zhang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. November 2010, 132(11): 111001.
https://doi.org/10.1115/1.4002551
Published Online: October 12, 2010
View Article titled, Modeling Material-Degradation-Induced Elastic Property of Tissue Engineering Scaffolds
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Topics: Finite element model, Mechanical properties, Modeling, Molecular weight, Tissue scaffolds, Young's modulus, Nanoparticles, Elasticity, Finite element analysis, Tissue engineering
Journal Articles

Peptide- and Aptamer-Functionalized Nanovectors for Targeted Delivery of Therapeutics

Todd O. Pangburn, Matthew A. Petersen, Brett Waybrant, Maroof M. Adil, Efrosini Kokkoli
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technology Review
J Biomech Eng. July 2009, 131(7): 074005.
https://doi.org/10.1115/1.3160763
Published Online: July 31, 2009
View Article titled, Peptide- and Aptamer-Functionalized Nanovectors for Targeted Delivery of Therapeutics
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Topics: Cancer, DNA, Drug delivery systems, Drugs, Nanoparticles, Proteins, Tumors, Vehicles, Patient treatment
Journal Articles

Nanoparticles for Thermal Cancer Therapy

Emily S. Day, Jennifer G. Morton, Jennifer L. West
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technology Review
J Biomech Eng. July 2009, 131(7): 074001.
https://doi.org/10.1115/1.3156800
Published Online: July 16, 2009
View Article titled, Nanoparticles for Thermal Cancer Therapy
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Topics: Cancer, Heating, Nanoparticles, Patient treatment, Tumors, Radiofrequency ablation, Biological tissues, Temperature
Journal Articles

Numerical Simulation of Au Nanoparticles Effect on the PCR Process

Chao Chen, Aili Zhang, Xiaodong Zhang, Jun Hu, Lisa X. Xu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. July 2009, 131(7): 074512.
https://doi.org/10.1115/1.3147746
Published Online: June 12, 2009
View Article titled, Numerical Simulation of Au Nanoparticles Effect on the PCR Process
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Topics: Nanoparticles, DNA
Journal Articles

An Adjustable Triple-Bifurcation Unit Model for Air-Particle Flow Simulations in Human Tracheobronchial Airways

C. Kleinstreuer, Z. Zhang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2009, 131(2): 021007.
https://doi.org/10.1115/1.3005339
Published Online: December 10, 2008
View Article titled, An Adjustable Triple-Bifurcation Unit Model for Air-Particle Flow Simulations in Human Tracheobronchial Airways
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Topics: Bifurcation, Nanoparticles, Particulate matter, Turbulence, Flow (Dynamics), Lung, Simulation
Journal Articles

Effects of Oral Airway Geometry Characteristics on the Diffusional Deposition of Inhaled Nanoparticles

Jinxiang Xi, P. Worth Longest
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2008, 130(1): 011008.
https://doi.org/10.1115/1.2838039
Published Online: February 7, 2008
View Article titled, Effects of Oral Airway Geometry Characteristics on the Diffusional Deposition of Inhaled Nanoparticles
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Topics: Aerosols, Flow (Dynamics), Nanoparticles, Particulate matter, Turbulence, Geometry
Journal Articles

Laminar Airflow and Nanoparticle or Vapor Deposition in a Human Nasal Cavity Model

H. Shi, C. Kleinstreuer, Z. Zhang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. October 2006, 128(5): 697–706.
https://doi.org/10.1115/1.2244574
Published Online: March 6, 2006
View Article titled, Laminar Airflow and Nanoparticle or Vapor Deposition in a Human Nasal Cavity Model
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Topics: Air flow, Cavities, Flow (Dynamics), Nanoparticles, Particulate matter, Transients (Dynamics)