Nonlinear 3-D models with fluid-structure interactions (FSI) based on in vitro experiments are introduced and solved by ADINA to perform flow and stress/strain analysis for stenotic arteries with lipid cores. Navier-Stokes equations are used as the governing equations for the fluid. Hyperelastic Mooney-Rivlin models are used for both the arteries and lipid cores. Our results indicate that critical plaque stress/strain conditions are affected considerably by stenosis severity, eccentricity, lipid pool size, shape and position, plaque cap thickness, axial stretch, pressure, and fluid-structure interactions, and may be used for possible plaque rupture predictions.
Issue Section:
Soft Tissue
Keywords:
Navier-Stokes equations,
haemodynamics,
stress analysis,
blood vessels,
diseases,
physiological models,
fracture,
biochemistry
Topics:
Flow (Dynamics),
Fluid structure interaction,
Pressure,
Stress,
Rupture,
Fluids,
Shear stress,
Shapes
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