The coupling of computational hemodynamics to measured translesional mean pressure gradients with an angioplasty catheter in human coronary stenoses was evaluated. A narrowed flow cross section with the catheter present effectively introduced a tighter stenosis than the enlarged residual stenoses after balloon angioplasty; thus elevating the pressure gradient and reducing blood flow during the measurements. For resting conditions with the catheter present, flow was believed to be about 40 percent of normal basal flow in the absence of the catheter, and for hyperemia, about 20 percent of elevated flow in the patient group. The computations indicated that the velocity field was viscous dominated and quasi-steady with negligible phase lag in the Δp(t) – u¯(t) relation during the cardiac cycle at the lower hydraulic Reynolds numbers and frequency parameter. Hemodynamic interactions with smaller catheter-based pressure sensors evolving in clinical use require subsequent study since artifactually elevated translesional pressure gradients can occur during measurements with current angioplasty catheters.
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June 1999
Technical Papers
Catheter Obstruction Effect on Pulsatile Flow Rate-Pressure Drop During Coronary Angioplasty
R. K. Banerjee,
R. K. Banerjee
Fluent, Inc., Lebanon, NH 03766
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L. H. Back,
L. H. Back
Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109
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M. R. Back,
M. R. Back
Division of Vascular Surgery, University of South Florida, College of Medicine, Tampa, FL 33606
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Y. I. Cho
Y. I. Cho
Mechanical Engineering and Mechanics Department, Drexel University, Philadelphia, PA 19104
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R. K. Banerjee
Fluent, Inc., Lebanon, NH 03766
L. H. Back
Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109
M. R. Back
Division of Vascular Surgery, University of South Florida, College of Medicine, Tampa, FL 33606
Y. I. Cho
Mechanical Engineering and Mechanics Department, Drexel University, Philadelphia, PA 19104
J Biomech Eng. Jun 1999, 121(3): 281-289 (9 pages)
Published Online: June 1, 1999
Article history
Received:
June 20, 1998
Revised:
December 14, 1998
Online:
October 30, 2007
Citation
Banerjee, R. K., Back, L. H., Back, M. R., and Cho, Y. I. (June 1, 1999). "Catheter Obstruction Effect on Pulsatile Flow Rate-Pressure Drop During Coronary Angioplasty." ASME. J Biomech Eng. June 1999; 121(3): 281–289. https://doi.org/10.1115/1.2798321
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