Trans-vaginal synthetic meshes have been commonly used to treat pelvic organ prolapse. Recently however, concerns related to the use of trans-vaginal mesh have arisen due to the high incidence of complications. The FDA received more than 3000 reports of complications related to these procedures between 2008 and 2010. Of the women who undergo this procedure, approximately 30% will require additional surgery within 4 years [1]. The most common complication reported was an erosion of the vaginal wall [2]. We hypothesize that mismatch between the mechanical properties of the vaginal tissue and the synthetic mesh lead to higher stresses in the vaginal tissue and subsequently to a higher risk of mesh erosion.

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