Cartilage tissue engineering (CTE) is a strategy of great interest and promise for the replacement of osteoarthritic (OA) cartilage. In CTE, chondrocytes are used to synthesize cartilage matrix products (predominantly glycosaminoglycans (GAG) and type II collagen). The aim for CTE is to develop engineered constructs with mechanical properties and biochemical composition comparable to native tissue, to reproduce its functional properties.
- Bioengineering Division
Binding and Release Kinetics of Glycosaminoglycans and Collagen in Engineered Cartilage Under TGF-β Supplementation
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Nims, RJ, Cigan, AD, Albro, MB, Hung, CT, & Ateshian, GA. "Binding and Release Kinetics of Glycosaminoglycans and Collagen in Engineered Cartilage Under TGF-β Supplementation." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions. Sunriver, Oregon, USA. June 26–29, 2013. V01BT28A010. ASME. https://doi.org/10.1115/SBC2013-14660
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