Atherosclerotic plaque rupture is believed to be associated with critical flow and stress/strain conditions. Image-based computational models have been developed to identify critical flow and stress/strain conditions in the plaque [1–3]. In vivo image-based coronary plaque modeling papers are relatively rare because clinical recognition of vulnerable coronary plaques has remained challenging . In this paper, a framework adopting intravascular ultrasound (IVUS) imaging with on-site pressure and flow measurements, biaxial mechanical testing and computational modeling is proposed to construct 3D coronary plaque for more accurate stress/strain predictions.
- Bioengineering Division
A Framework to Assess Human Coronary Plaque Vulnerability Using Intravascular Ultrasound, On-Site Pressure, Angiography, and Anisotropic FSI Models
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Liu, H, Cai, M, Yang, C, Zheng, J, Bach, R, Kural, M, Billiar, K, Muccigrosso, D, Lu, D, & Tang, D. "A Framework to Assess Human Coronary Plaque Vulnerability Using Intravascular Ultrasound, On-Site Pressure, Angiography, and Anisotropic FSI Models." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 909-910. ASME. https://doi.org/10.1115/SBC2012-80040
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