Arteries respond to long-term alterations in arterial pressure and blood flow by changing geometry, structure, and composition. This response is termed as remodeling and plays an important role in normal arterial physiology and in the genesis and progression of certain vascular disorders. In healthy mature arteries, remodeling represents an adaptive process that tends to restore the local mechanical environment of vascular cells to baseline levels and thereby to preserve the optimal performance of the arterial function. The objective of this study is twofold — to develop a general method for calculation the remodeling outputs of an artery considered as a two-layered tube; and to provide results for adaptive and maladaptive remodeling of a coronary artery.
- Bioengineering Division
Calculation of the Outcomes of Adaptive and Maladaptive Remodeling of Arteries Subjected to Sustained Hypertension Using a 3D Two-Layered Model
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Rachev, A, Taylor, WR, & Vito, RP. "Calculation of the Outcomes of Adaptive and Maladaptive Remodeling of Arteries Subjected to Sustained Hypertension Using a 3D Two-Layered Model." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 1011-1012. ASME. https://doi.org/10.1115/SBC2012-80092
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