A principal concern in diabetes is the increased risk of vascular disease associated with unregulated blood glucose. Endothelial cells that line the vasculature are dysfunctional in hyperglycemia. The high glucose environment promotes basement membrane protein glycation and enhanced cross-linking, which can increase stiffness and may alter endothelial cell response to strain.
Volume Subject Area:
Poster Session II: Student Paper Competition (PhD Level)
Topics:
Endothelial cells,
Membranes,
Blood glucose,
Diabetes,
Diseases,
Glucose,
Proteins,
Risk,
Stiffness
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