Otitis media (OM) is the most commonly diagnosed disorder in young children and cost the US economy ∼$5 billion dollars annually. Although the primary etiology responsible for the persistence of OM conditions is a dysfunctional Eustachian tube (ET), the biomechanical mechanisms responsible for ET dysfunction are not well established. The ET is a collapsible, respiratory airway which connects the nasopharynx with the middle ear (ME). The ET normally exists in a closed state and must be periodically opened in order to clear ME fluids and ventilate the ME. The inability to open the ET results in painful sub-ambient ME pressures, fluid accumulation in the ME and the inflammation of the ME mucosa (i.e. OM).
Finite Element Analysis of Clinical Pressure-Flow Waveforms in a Collapsed Respiratory Airway
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Bell, ED, & Ghadiali, SN. "Finite Element Analysis of Clinical Pressure-Flow Waveforms in a Collapsed Respiratory Airway." Proceedings of the ASME 2007 Summer Bioengineering Conference. ASME 2007 Summer Bioengineering Conference. Keystone, Colorado, USA. June 20–24, 2007. pp. 309-310. ASME. https://doi.org/10.1115/SBC2007-175329
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