The cell alignment in a smooth muscle tissue plays a significant role in determining its mechanical properties. In addition to shortening strain, the off-axis cell orientation θ also modify the shear stress relationship significantly. A simulation model based on finite element analysis is developed to study the effect of stresses of tracheal smooth muscle tissue when its cells are orientated off-axially. Results obtained indicate that the maximum shear stress values of tracheal smooth muscle tissue at 45% strain are 2.5 times the values at 20% strain for all three off-axis orientation values θ = 15°, 30° and 45°.
Effect of Off-Axis Cell Orientation in Smooth Muscle Tissue
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Sarma, PA, Pidaparti, RM, & Meiss, RA. "Effect of Off-Axis Cell Orientation in Smooth Muscle Tissue." Proceedings of the ASME 2003 International Mechanical Engineering Congress and Exposition. Advances in Bioengineering. Washington, DC, USA. November 15–21, 2003. pp. 319-320. ASME. https://doi.org/10.1115/IMECE2003-42979
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