Familiar near-term goals for buildings include making them “net zero ready,” followed by “net zero energy,” in which the actual annual source energy consumption is balanced by onsite renewable energy, and finally “carbon neutral,” in which both the operating and the embodied sources of carbon are taken into account. Assuming that buildings can achieve carbon neutrality, what then? What are the other desired outcomes for ubiquitous building services? The U.S. Department of Energy Building Technologies Office, in collaboration with the Pacific Northwest National Laboratory, led a discussion of the desired long-term future of typical U.S. buildings through a series of panel discussions, webinars, and workshops. The objective is to define a set of building attributes, complete with corresponding metrics and targets that can serve as the long-term goal for residential and commercial buildings in the U.S. These attributes include not only energy and carbon emissions but also the health, wellbeing, and productivity of building occupants, how buildings integrate with the larger community and ecosystem around them, how buildings are constructed and/or manufactured to optimize resource use, and their resilience and flexibility to adapt to changes and be repurposed to meet future needs. Can we transform the way we design, build, and operate buildings to achieve these short-term and long-term goals? How may technology breakthroughs and innovative collaborations shift the paradigm? This vision, which will be published later in a separate article, aims to inspire scientists from various fields to explore revolutionary and integrated ways to truly achieve sustainable, healthy, adaptive, and productive buildings.