Within the MED-CSD project, feasibility studies of integrated hybrid concentrating solar power (CSP) and seawater desalination (DES) plants were carried out in selected locations in Morocco, Italy, Cyprus, Egypt and Gaza/West Bank. After a review on CSP and desalination technologies, ten typical sites within the five partner countries have been selected. For each location, a CSP-DES plant was modeled. The model bases on hourly time series of solar irradiance, ambient temperature, as well as wind speed and includes local seasonal and hourly load curves for power and water. Surplus thermal energy from the solar field is fed into the energy storage, so that operation is possible at night and during cloud transients; gaps between demand and solar power production are covered by cofiring with fossil fuel. Different plant components (solar field collectors and desalination technologies) have been compared. A techno-economic model is applied in order to analyze the economic feasibility and the required financial framework conditions of the projects. Furthermore, an analysis of the market potential of concentrating solar power for sea water desalination in the Mediterranean Region and socio-economic and environmental impact analyses were implemented.